Sleep Benefits Long-Term Memory Redding CA

Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory.

Kimberly Ann Page, MD
(530) 246-2207
1950 Rosaline Ave Ste B
Redding, CA
Specialties
Neurological Surgery
Gender
Female
Education
Medical School: Univ Of Nv Sch Of Med, Reno Nv 89557
Graduation Year: 1987

Data Provided by:
Jamsid Saleh
(530) 243-6811
3652 Eureka Way
Redding, CA
Specialty
Neurosurgery

Data Provided by:
Guy Corkill, MD
(916) 243-4886
2107 Airpark Dr
Redding, CA
Specialties
Neurological Surgery
Gender
Male
Education
Medical School: Univ Of Cambridge, Sch Of Cli Med, Cambridge (352-03 Prior 1/71)
Graduation Year: 1962

Data Provided by:
Kym Lynette Chandler, MD
(530) 243-2579
1839 Sonoma St
Redding, CA
Specialties
Neurological Surgery
Gender
Female
Education
Medical School: Univ Of Md Sch Of Med, Baltimore Md 21201
Graduation Year: 1985

Data Provided by:
Gary J Rowe
(530) 241-2643
1555 Court St
Redding, CA
Specialty
Neurology

Data Provided by:
Richard Duane Karem, MD
(530) 244-1332
1844 South St
Redding, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Univ Of Ca, Davis, Sch Of Med, Davis Ca 95616
Graduation Year: 1981

Data Provided by:
Harvinder S Birk, MD
2015 Shasta St Ste 2
Redding, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Dayanand Med Coll, Punjab Univ, Ludhiana, Punjab, India
Graduation Year: 1979

Data Provided by:
Afrassiab Guity, MD
(530) 244-6246
2851 Park Marina Dr
Redding, CA
Specialties
Neurological Surgery
Gender
Male
Education
Medical School: Teheran Univ, Fac Of Med, Teheran, Iran
Graduation Year: 1968

Data Provided by:
Gary James Rowe, MD
1555 Court St
Redding, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Med Coll Of Wi, Milwaukee Wi 53226
Graduation Year: 1964

Data Provided by:
Richard D Karem
(530) 244-1332
1844 South St
Redding, CA
Specialty
Neurosurgery

Data Provided by:
Data Provided by:

Sleep Benefits Long-Term Memory

Provided By:

Researchers at MIT have confirmed that sleep is essential for long-term storage of memories.

Their study showed that mice unable to "replay" their awake experiences while asleep remember them less well than mice who can perform this function. Scientists from the RIKEN-MIT Center for Neural Circuit Genetics at MITs Picower Institute for Learning and Memory report their findings in the June 24 issue of Neuron.

"Our work demonstrates the molecular link between post-experience sleep and the establishment of long-term memory of that experience," study author Susumu Tonegawa, Picower Professor of Biology and Neuroscience, said in a school news release. "Ours is the first study to demonstrate this link between memory replay and memory consolidation. The sleeping brain must replay experiences like video clips before they are transformed from short-term into long-term memories."

Researchers tested their theories by implanting electrodes in the brains of mice that were fed a special diet to disrupt their trisynaptic circuits. These circuits, found in the hippocampus, are now confirmed to play a crucial role in processing memories before they move on to other regions for storage.

While they were awake and running in a maze, the mice formed cells that fired in recognition of their newly learned task -- negotiating the maze. Those cells fired in similar sequences during their post-run sleep. Mice whose trisynaptic circuits functioned properly during sleep remembered the maze longer than those whose trisynaptic circuits were disabled, researchers reported.

"Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory," said Tonegawa.

More information

Learn more about this and other studies at The Picower Institute.

SOURCE: MIT News Office, news release, June 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com