Sleep Benefits Long-Term Memory Stockton CA

Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory.

Nancy Santos MD
(209) 339-8800
999 S Fairmont Ave
Lodi, CA
Specialties
Neurology

Data Provided by:
Abha M Oshtory, MD
(209) 944-5730
2626 N California St # St-1
Stockton, CA
Specialties
Neurology
Gender
Female
Education
Medical School: Grant Med Coll, Univ Of Bombay, Bombay, Maharashtra, India
Graduation Year: 1970

Data Provided by:
Abha M Oshtory
(209) 944-5733
2626 N California St
Stockton, CA
Specialty
Neurology

Data Provided by:
Meherji A Oshtory
(209) 944-5730
2626 N Califonia St
Stockton, CA
Specialty
Neurology

Data Provided by:
F Karl Gregorius, MD
(209) 943-0305
2209 N California St
Stockton, CA
Specialties
Neurological Surgery
Gender
Male
Education
Medical School: Loma Linda Univ Sch Of Med, Loma Linda Ca 92350
Graduation Year: 1967

Data Provided by:
Moris Senegor, MD
(209) 943-0305
2209 N California St
Stockton, CA
Specialties
Neurological Surgery
Gender
Male
Education
Medical School: Univ Of Chicago, Pritzker Sch Of Med, Chicago Il 60637
Graduation Year: 1982

Data Provided by:
Warren David Clift, MD
(209) 466-3551
2815 N California St
Stockton, CA
Specialties
Neurology
Gender
Male
Education
Medical School: New York Med Coll, Valhalla Ny 10595
Graduation Year: 1962
Hospital
Hospital: St Josephs Med Ctr, Stockton, Ca
Group Practice: Stockton Neurological Medical

Data Provided by:
Meherji A Oshtory, MD
(209) 944-5730
2626 N California St
Stockton, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Grant Med Coll, Univ Of Bombay, Bombay, Maharashtra, India
Graduation Year: 1966

Data Provided by:
Dean Strom Karnaze, MD
545 E Cleveland St Ste B
Stockton, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Univ Of Ks Sch Of Med, Kansas City Ks 66103
Graduation Year: 1973

Data Provided by:
John Henning Campion, MD
Stockton, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Univ Of Ca, Irvine, Ca Coll Of Med, Irvine Ca 92717
Graduation Year: 1975

Data Provided by:
Data Provided by:

Sleep Benefits Long-Term Memory

Provided By:

Researchers at MIT have confirmed that sleep is essential for long-term storage of memories.

Their study showed that mice unable to "replay" their awake experiences while asleep remember them less well than mice who can perform this function. Scientists from the RIKEN-MIT Center for Neural Circuit Genetics at MITs Picower Institute for Learning and Memory report their findings in the June 24 issue of Neuron.

"Our work demonstrates the molecular link between post-experience sleep and the establishment of long-term memory of that experience," study author Susumu Tonegawa, Picower Professor of Biology and Neuroscience, said in a school news release. "Ours is the first study to demonstrate this link between memory replay and memory consolidation. The sleeping brain must replay experiences like video clips before they are transformed from short-term into long-term memories."

Researchers tested their theories by implanting electrodes in the brains of mice that were fed a special diet to disrupt their trisynaptic circuits. These circuits, found in the hippocampus, are now confirmed to play a crucial role in processing memories before they move on to other regions for storage.

While they were awake and running in a maze, the mice formed cells that fired in recognition of their newly learned task -- negotiating the maze. Those cells fired in similar sequences during their post-run sleep. Mice whose trisynaptic circuits functioned properly during sleep remembered the maze longer than those whose trisynaptic circuits were disabled, researchers reported.

"Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory," said Tonegawa.

More information

Learn more about this and other studies at The Picower Institute.

SOURCE: MIT News Office, news release, June 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com