Sleep Benefits Long-Term Memory Visalia CA

Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory.

Thomas Evans Hoyt, MD
(559) 739-1300
PO Box 1351
Visalia, CA
Specialties
Neurological Surgery
Gender
Male
Education
Medical School: Wayne State Univ Sch Of Med, Detroit Mi 48201
Graduation Year: 1977

Data Provided by:
Bernard P Rudis, MD
(559) 627-5535
2431 W Caldwell Ave
Visalia, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Creighton Univ Sch Of Med, Omaha Ne 68178
Graduation Year: 1959

Data Provided by:
Richard Leo Pantera
(559) 625-1691
623 W Willow
Visalia, CA
Specialty
Neurology

Data Provided by:
Zoltan Mocsary
(559) 738-7500
5400 W Hillsdale Ave
Visalia, CA
Specialty
Neurology

Data Provided by:
Joyce Ceres Jones, MD
(559) 738-7500
5400 W Hillsdale Ave
Visalia, CA
Specialties
Neurology
Gender
Female
Education
Medical School: Univ Of Ct Sch Of Med, Farmington Ct 06032
Graduation Year: 1978

Data Provided by:
Yao Liu
(559) 635-1118
5533 W. Hillsdale
Visalia, CA
Specialty
Neurology

Data Provided by:
Richard Leo Pantera, MD
(559) 625-1691
623 W Willow Ave
Visalia, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1973

Data Provided by:
Boota S Chahil
(559) 625-0202
117 N Akers St
Visalia, CA
Specialty
Neurology

Data Provided by:
Boota Singh Chahil, MD
(559) 625-0202
5433 W Hillsdale Ave
Visalia, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Patliputra Med Coll, Ranchi Univ, Dhanbad, Bihar, India
Graduation Year: 1982

Data Provided by:
David Laurence Roberts, MD
840 S Akers St
Visalia, CA
Specialties
Neurology
Gender
Male
Education
Medical School: Univ Of Southern Ca Sch Of Med, Los Angeles Ca 90033
Graduation Year: 1964

Data Provided by:
Data Provided by:

Sleep Benefits Long-Term Memory

Provided By:

Researchers at MIT have confirmed that sleep is essential for long-term storage of memories.

Their study showed that mice unable to "replay" their awake experiences while asleep remember them less well than mice who can perform this function. Scientists from the RIKEN-MIT Center for Neural Circuit Genetics at MITs Picower Institute for Learning and Memory report their findings in the June 24 issue of Neuron.

"Our work demonstrates the molecular link between post-experience sleep and the establishment of long-term memory of that experience," study author Susumu Tonegawa, Picower Professor of Biology and Neuroscience, said in a school news release. "Ours is the first study to demonstrate this link between memory replay and memory consolidation. The sleeping brain must replay experiences like video clips before they are transformed from short-term into long-term memories."

Researchers tested their theories by implanting electrodes in the brains of mice that were fed a special diet to disrupt their trisynaptic circuits. These circuits, found in the hippocampus, are now confirmed to play a crucial role in processing memories before they move on to other regions for storage.

While they were awake and running in a maze, the mice formed cells that fired in recognition of their newly learned task -- negotiating the maze. Those cells fired in similar sequences during their post-run sleep. Mice whose trisynaptic circuits functioned properly during sleep remembered the maze longer than those whose trisynaptic circuits were disabled, researchers reported.

"Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory," said Tonegawa.

More information

Learn more about this and other studies at The Picower Institute.

SOURCE: MIT News Office, news release, June 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com