Treatments for Sun-Damaged Skin Bakersfield CA

Fluorouracil is used to treat cancers of the colon, head and neck, pancreas and other organs in Bakersfield. Changes in skin appearance have been noted in people undergoing treatment with systemic fluorouracil, and this led to the development of a skin cream that contains the cancer drug.

Howard Yuanhao Chang, MD
(661) 327-3638
2120 Truxtun Ave
Bakersfield, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Harvard Med Sch, Boston Ma 02115
Graduation Year: 2000

Data Provided by:
Lynn Cranmer
(800) 353-5400
3733 San Dimas St
Bakersfield, CA
Specialty
Dermatology

Data Provided by:
Norman Emanuel LeVan
(661) 324-5392
1828 28th St
Bakersfield, CA
Specialty
Dermatology

Data Provided by:
Arun Softa MD Ambika Softa MD
(661) 716-2600
2005 17th St
Bakersfield, CA
 
Pacific West Dermatology, Plastic Surgery Laser
(661) 323-3900
2920 F St, Ste B1
Bakersfield, CA
 
Sherilyn Ann Baughman, MD
(559) 781-1812
2215 G St
Bakersfield, CA
Specialties
Dermatology
Gender
Female
Education
Medical School: Loma Linda Univ Sch Of Med, Loma Linda Ca 92350
Graduation Year: 1981

Data Provided by:
A Head of Time Beauty Salon
(661) 328-0614
1920 Eye St
Bakersfield, CA
 
Michael A MacDuff
(661) 324-1312
2215 G St
Bakersfield, CA
Specialty
Dermatology

Data Provided by:
Michael Allan MacDuff, MD
(661) 324-1312
2215 G St
Bakersfield, CA
Specialties
Dermatology, Dermatopathology
Gender
Male
Education
Medical School: New York Med Coll, Valhalla Ny 10595
Graduation Year: 1968

Data Provided by:
Michael Allan Mac Duff, MD
(661) 324-1312
2215 G St
Bakersfield, CA
Specialties
Dermatology, Dermatopathology
Gender
Male
Education
Medical School: New York Med Coll, Valhalla Ny 10595
Graduation Year: 1968
Hospital
Hospital: Riverview Med Ctr, Red Bank, Nj
Group Practice: Kern Dermatology Medical Group

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Treatments for Sun-Damaged Skin

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MONDAY, June 15 (HealthDay News) -- Applying the chemotherapy drug fluorouracil to skin might help improve the appearance of sun-damaged areas and reduce potentially precancerous patches, according to a small, new study.

Fluorouracil is used to treat cancers of the colon, head and neck, pancreas and other organs. Changes in skin appearance have been noted in people undergoing treatment with systemic fluorouracil, and this led to the development of a skin cream that contains the cancer drug.

The new study included 21 healthy volunteers with sun-damaged skin and actinic keratoses -- skin lesions that could develop into skin cancer -- on their faces. The participants applied 5 percent fluorouracil cream to their faces twice daily for two weeks.

The researchers said that the number of actinic keratoses declined from an average of 11.6 lesions per person to an average of 1.5 lesions. There were also improvements in aging-related damage, including wrinkling and dark skin spots.

The study, funded by Valeant Pharmaceuticals International, was published in the June issue of the journal Archives of Dermatology.

"For patients in whom a course of topical fluorouracil is indicated for the treatment of actinic keratoses, there will likely be the additional benefit of a restorative effect from sun damage; this may provide further motivation for these patients to undergo the rigorous treatment," concluded Dr. Dana L. Sachs, of the University of Michigan Medical School, and colleagues.

"It is possible that for some patients topical fluorouracil may have an important role against photo-aging," they wrote. "For others, however, it may not be cosmetically acceptable given that a standard course of therapy may last two to three weeks and the ensuring reaction can persist for several more weeks. Undoubtedly, there will be patients who desire a therapy such as topical fluorouracil for cosmetic purposes given the relatively low cost of this therapy compared with ablative laser resurfacing."

More information

The U.S. National Cancer Institute offers skin cancer prevention tips.

SOURCE: JAMA/Archives journals, news release, June 15, 2009

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