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Treatments for Sun-Damaged Skin Fresno CA

Fluorouracil is used to treat cancers of the colon, head and neck, pancreas and other organs in Fresno. Changes in skin appearance have been noted in people undergoing treatment with systemic fluorouracil, and this led to the development of a skin cream that contains the cancer drug.

Fresno Cosmetic Dermatology
(559) 448-4745
4785 N 1st St
Fresno, CA
 
Syed M Pervaiz, MD
(559) 674-4533
5151 N Palm Ave
Fresno, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Univ Of Miami Sch Of Med, Miami Fl 33101
Graduation Year: 1988

Data Provided by:
Jane Flora Kardashian, MD
(559) 435-0337
6769 N Fresno St Ste 100
Fresno, CA
Specialties
Dermatology
Gender
Female
Languages
French, Armenian
Education
Medical School: Umdnj-New Jersey Med Sch, Newark Nj 07103
Graduation Year: 1979
Hospital
Hospital: Fresno Comm Med Ctr, Fresno, Ca

Data Provided by:
David Ray Taylor
(559) 266-9906
5640 N Fresno St
Fresno, CA
Specialty
Dermatology

Data Provided by:
Gerald Eugene Peters, MD
(559) 432-3333
6700 N 1st St Ste 131
Fresno, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Univ Of Cincinnati Coll Of Med, Cincinnati Oh 45267
Graduation Year: 1960

Data Provided by:
Robert Dale Morris, MD
(559) 448-4745
4785 N 1st St
Fresno, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Univ Of Ca, San Francisco, Sch Of Med, San Francisco Ca 94143
Graduation Year: 1973

Data Provided by:
Regina C Hamlin, MD
(559) 432-1821
4005 N Fresno St
Fresno, CA
Specialties
Dermatology
Gender
Female
Education
Medical School: Univ Of Ca, San Francisco, Sch Of Med, San Francisco Ca 94143
Graduation Year: 1970

Data Provided by:
David Ray Taylor, MD
5640 N Fresno St Ste 110
Fresno, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Univ Of Southern Ca Sch Of Med, Los Angeles Ca 90033
Graduation Year: 1945

Data Provided by:
Eric Leif Hanson, MD
(919) 966-0785
6011 N Fresno St
Fresno, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Tufts Univ Sch Of Med, Boston Ma 02111
Graduation Year: 1994

Data Provided by:
Jane F Kardashian
(559) 435-0337
6769 N Fresno St
Fresno, CA
Specialty
Dermatology

Data Provided by:
Data Provided by:

Treatments for Sun-Damaged Skin

Provided By:

MONDAY, June 15 (HealthDay News) -- Applying the chemotherapy drug fluorouracil to skin might help improve the appearance of sun-damaged areas and reduce potentially precancerous patches, according to a small, new study.

Fluorouracil is used to treat cancers of the colon, head and neck, pancreas and other organs. Changes in skin appearance have been noted in people undergoing treatment with systemic fluorouracil, and this led to the development of a skin cream that contains the cancer drug.

The new study included 21 healthy volunteers with sun-damaged skin and actinic keratoses -- skin lesions that could develop into skin cancer -- on their faces. The participants applied 5 percent fluorouracil cream to their faces twice daily for two weeks.

The researchers said that the number of actinic keratoses declined from an average of 11.6 lesions per person to an average of 1.5 lesions. There were also improvements in aging-related damage, including wrinkling and dark skin spots.

The study, funded by Valeant Pharmaceuticals International, was published in the June issue of the journal Archives of Dermatology.

"For patients in whom a course of topical fluorouracil is indicated for the treatment of actinic keratoses, there will likely be the additional benefit of a restorative effect from sun damage; this may provide further motivation for these patients to undergo the rigorous treatment," concluded Dr. Dana L. Sachs, of the University of Michigan Medical School, and colleagues.

"It is possible that for some patients topical fluorouracil may have an important role against photo-aging," they wrote. "For others, however, it may not be cosmetically acceptable given that a standard course of therapy may last two to three weeks and the ensuring reaction can persist for several more weeks. Undoubtedly, there will be patients who desire a therapy such as topical fluorouracil for cosmetic purposes given the relatively low cost of this therapy compared with ablative laser resurfacing."

More information

The U.S. National Cancer Institute offers skin cancer prevention tips.

SOURCE: JAMA/Archives journals, news release, June 15, 2009

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