Treatments for Sun-Damaged Skin Stockton CA

Fluorouracil is used to treat cancers of the colon, head and neck, pancreas and other organs in Stockton. Changes in skin appearance have been noted in people undergoing treatment with systemic fluorouracil, and this led to the development of a skin cream that contains the cancer drug.

Steven H Goldberg, MD
(858) 573-5688
2216 N California St
Stockton, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Univ Of Tx Southwestern Med Ctr At Dallas, Med Sch, Dallas Tx 75235
Graduation Year: 1987

Data Provided by:
Gerald N Bock
(209) 956-4260
1617 St Marks Plaza
Stockton, CA
Specialty
Dermatology

Data Provided by:
David Randall Bruce, DO
(209) 951-1133
4553 Quail Lakes Dr
Stockton, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Kirksville Coll Of Osteo Med, Kirksville Mo 63501
Graduation Year: 1981

Data Provided by:
Kyle Wayne Herbold
(209) 951-1133
4553 Quail Lakes Dr
Stockton, CA
Specialty
Dermatology

Data Provided by:
California Skin Laser Center
(209) 957-0720
1617 Saint Marks Plz
Stockton, CA
 
California Vein Vascular Institute
(209) 462-8346
2216 N California St, Ste C
Stockton, CA
 
Walter Stanley Yourchek
(209) 951-1133
4553 Quail Lakes Dr
Stockton, CA
Specialty
Dermatology

Data Provided by:
Prescott Jr, Clinton E DO - Central Valley Dermatology
(209) 477-7546
423 Lincoln Ctr
Stockton, CA
 
Stuart Ira Jacobs, MD
(209) 957-6662
5345 N El Dorado St Ste 12
Stockton, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: Univ Of Mi Med Sch, Ann Arbor Mi 48109
Graduation Year: 1972

Data Provided by:
Walter S Yourchek, MD
(209) 951-1133
4553 Quail Lakes Dr
Stockton, CA
Specialties
Dermatology
Gender
Male
Education
Medical School: George Washington Univ Sch Of Med & Hlth Sci, Washington Dc 20037
Graduation Year: 1964

Data Provided by:
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Treatments for Sun-Damaged Skin

Provided By:

MONDAY, June 15 (HealthDay News) -- Applying the chemotherapy drug fluorouracil to skin might help improve the appearance of sun-damaged areas and reduce potentially precancerous patches, according to a small, new study.

Fluorouracil is used to treat cancers of the colon, head and neck, pancreas and other organs. Changes in skin appearance have been noted in people undergoing treatment with systemic fluorouracil, and this led to the development of a skin cream that contains the cancer drug.

The new study included 21 healthy volunteers with sun-damaged skin and actinic keratoses -- skin lesions that could develop into skin cancer -- on their faces. The participants applied 5 percent fluorouracil cream to their faces twice daily for two weeks.

The researchers said that the number of actinic keratoses declined from an average of 11.6 lesions per person to an average of 1.5 lesions. There were also improvements in aging-related damage, including wrinkling and dark skin spots.

The study, funded by Valeant Pharmaceuticals International, was published in the June issue of the journal Archives of Dermatology.

"For patients in whom a course of topical fluorouracil is indicated for the treatment of actinic keratoses, there will likely be the additional benefit of a restorative effect from sun damage; this may provide further motivation for these patients to undergo the rigorous treatment," concluded Dr. Dana L. Sachs, of the University of Michigan Medical School, and colleagues.

"It is possible that for some patients topical fluorouracil may have an important role against photo-aging," they wrote. "For others, however, it may not be cosmetically acceptable given that a standard course of therapy may last two to three weeks and the ensuring reaction can persist for several more weeks. Undoubtedly, there will be patients who desire a therapy such as topical fluorouracil for cosmetic purposes given the relatively low cost of this therapy compared with ablative laser resurfacing."

More information

The U.S. National Cancer Institute offers skin cancer prevention tips.

SOURCE: JAMA/Archives journals, news release, June 15, 2009

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